The NFL returns to Amazon Prime on Thursday, Sept. 29, when the Indianapolis Colts battle the Denver Broncos. The game will be live streamed on Prime Video (free trial).

Russell Wilson and Matt Ryan can sure feel each other’s pain.

None of the nine NFL teams that changed quarterbacks this season has a winning record heading into October.

Two of them square off Thursday night when Ryan’s beleaguered Indianapolis Colts (1-2-1) visit Wilson’s banged-up Denver Broncos (2-2).

Both QBs have found a rough transition to their new teams and both are missing key offensive and defensive players on a short week.

Ryan has eight turnovers in four games, has been sacked 15 times and fumbled nine times in his first season since leaving Atlanta. Wilson is off to the slowest start of his career with just four TD passes in his first season out of Seattle.

Wilson, however, has lost some of those teammates, notably wide receiver Tim Patrick and featured running back Javonte Williams to injured knees. Also out for at least a month with an injured knee is pass-rushing free agent acquisition Randy Gregory.

The Colts ruled out the NFL’s reigning rushing champ, Jonathan Taylor (toe, ankle) and playmaking safety Julian Blackmon (ankle). In concussion protocol are three-time All-Pro linebacker Shaquille Leonard and defensive lineman Tyquan Lewis.

Injuries or not, it’s little surprise that Ryan and Wilson are off to slow starts with their new teams as are Marcus Mariota in Atlanta, Baker Mayfield in Charlotte, Carson Wentz in Washington and Jacoby Brissett in Cleveland. Mitch Trubisky was benched in Pittsburgh for rookie Kenny Pickett after succeeding Ben Roethlisberger and going 1-3.

When is Colts-Broncos?

The Denver Broncos and Indianapolis Colts play at 7:15 p.m. (8:15 p.m. ET) on Thursday, Oct. 6. The pregame starts at 6 p.m. (7 p.m. ET).

Will it be live streamed?

The game will be carried by Amazon Prime Video, which offers a free trial. The game will be called by play-by-play announcer Al Michaels, analyst Kirk Herbstreit, reporter Kaylee Hartung, Pro Football Hall of Famer Tony Gonzalez, All-Pro cornerback Richard Sherman and NFL quarterback Ryan Fitzpatrick.

Will it be televised?

The Dolphins and Bengals will not be broadcast on traditional TV.

Preview

GROUNDED GAME: The Broncos had been feeling good about their disruptive defense until losing Gregory and watching Raiders running back Josh Jacobs gash them for 144 yards on 28 carries Sunday.

“Sometimes people get you,” Broncos coach Nathaniel Hackett said. “I think for us, it’s kind of like how the offense is: don’t try to make a play, just trust the system and know that the plays will come to you. It’s the same thing with the offense. Everybody wants it so bad and wants to do something special, but that will happen within the defense, within the offense and special teams.”

MILE HIGH MYSTIQUE: Colts coach Frank Reich didn’t even mention altitude when preparing his team this week. They did light work and he explained the focus needed to be not on elevation but execution.

“There was always that mystique about going out there,” Reich said. “I think what we’ve seen over the years is that it’s not the factor you think it’s going to be.”

SLOW STARTERS: The Colts aren’t just the NFL’s lowest-scoring team, they’re one of the league’s slowest-starting teams. They’ve been outscored 65-23 in the first half this season and have trailed at halftime of all four games.

“I think we’re close, I really do,” Ryan said. “The good has been good. It needs to show up more consistently.”

The Associated Press contributed to this report.