A Birmingham-based company led a long list of decliners Friday on our Birmingham and Alabama Stock Report.

Medical Properties Trust, the real estate investment trust that focuses on health care facilities, sunk 6.1% to fall narrowly close to a 52-week low.

Louisiana-Pacific led a small contingent of gainers at 2.1%.

Birmingham-based ProAssurance scored a 1.9% jump.

Overall, U.S. stocks mostly fell Friday after fears about war in the Middle East collided in financial markets with hopes for stronger profits at big U.S. companies.

Oil prices leaped, and Treasury yields fell after Israel’s military ordered the evacuation of northern Gaza ahead of a possible ground invasion, according to the United Nations, which warned of potentially “devastating humanitarian consequences.” But several U.S. banking giants at the same time said their profits during the summer were better than feared, which offered hope on Wall Street for an earning reporting season that may deliver the first growth for big companies in a year.