Christina Applegate rarely leaves home as a result of her multiple sclerosis, the former “Married with Children” star revealed.

“If people saw what my life was like on the daily, they wouldn’t they wouldn’t be able to do it. Because I can sometimes not do it. It’s really, really hard,” Applegate said Monday on “Conan O’Brien Needs a Friend.”

“I don’t really leave the house anymore,” Applegate added.

The 53-year-old was diagnosed with multiple sclerosis in 2021 and is often asked the same question.

“How did you get it? … Meaning, I must have done something wrong in my life to have this disease. I did it to myself,” she said.

“It’s, like, I had breast cancer as well, so, ‘Oh, you must have done something.’ That stigma is — I’m used to it now, but it was for a while, like, was so hard to swallow because why the f— would you think that I would do something to have this?”

Mark Heim is a reporter for The Alabama Media Group. Follow him on Twitter @Mark_Heim. He can be heard on “The Opening Kickoff” on WNSP-FM 105.5 FM in Mobile or on the free Sound of Mobile App from 6 to 9 a.m. daily.