Seth Meyers again has Alabama in his crosshairs.

A week after the late night host cited Dolly Parton in ‘Closer Look’ at Alabama frozen embryo ruling, the comedian posed the following question: “Why are Republicans allowed to s–t all over liberal cities while Democrats never s–t on red states?

He then cited homicide statistics that show New York City’s rate is 4.8 per 100,000, while Alabama’s rate is three times that at 15.9 per 100,000.

“But you never hear Joe Biden s–t all over Tuscaloosa.”

Meyers then did an impersonation of Biden, claiming “Tuscaloosa is a hell hole.”

“There’s a Crimson Tide alright,” he joked, “from all the murders. No joke. No joke.” He then took a lick of a pretend ice cream cone.

Take a look at the segment below.

Meanwhile, Biden is set to use his State of the Union on Thursday address to promote his vision for a second term to a dispirited electorate who question whether he’s up to the job and to warn that GOP front-runner Donald Trump would be a dangerous alternative.

Mark Heim is a reporter for The Alabama Media Group. Follow him on Twitter @Mark_Heim. He can be heard on “The Opening Kickoff” on WNSP-FM 105.5 FM in Mobile or on the free Sound of Mobile App from 6 to 9 a.m. daily.