March Madness 2025 continues on Friday, March 21, with 16 first-round NCAA men’s basketball tournament games at a variety of venues around the country.

Among those teams in action are No. 1 seeds Florida and Duke, along with traditional powers such as Kentucky, Michigan State, Connecticut and North Carolina. Alabama and Troy also take the court, as do SEC entries Mississippi State, Ole Miss and Oklahoma.

Here are the 16 first-round NCAA tournament games that take place on Friday, March 21, 2025, with tip-off times and television information (all times Central):

EAST: No. 8 Mississippi State (21-12) vs. No. 9 Baylor (19-14), 11:15 a.m., CBS

SOUTH: No. 3 Iowa State (24-9) vs. No. 14 Lipscomb (25-9), 12:30 p.m., TNT

WEST: No. 5 Memphis (29-5) vs. No. 12 Colorado State (25-9), 1 p.m., TBS

EAST: No. 1 Duke (31-3) vs. No. 16 Mount St. Mary’s (23-12), 1:50 p.m., CBS

SOUTH: No. 6 Ole Miss (22-11) vs. No. 11 North Carolina (23-13), 3:05 p.m., TNT

WEST: No. 4 Maryland (25-8) vs. No. 13 Grand Canyon (26-7), 3:35 p.m., TBS

WEST: No. 1 Florida (30-4) vs. No. 16 Norfolk State (24-10), 5:50 p.m., TNT

MIDWEST: No. 3 Kentucky (22-11) vs. No. 14 Troy (23-10), 6:10 p.m., CBS

SOUTH: No. 7 Marquette (23-10) vs. No. 10 New Mexico (26-7), 6:25 p.m., TBS

EAST: No. 4 Arizona (22-12) vs. No. 13 Akron (28-6), 6:35 p.m., truTV

WEST: No. 8 Connecticut (23-10) vs. No. 9 Oklahoma (20-13), 8:25 p.m., TNT

MIDWEST: No. 6 Illinois (21-12) vs. No. 11 Xavier (22-11), 8:45 p.m., CBS

SOUTH: No. 2 Michigan State (27-9) vs. No. 15 Bryant (23-11), 9 p.m., TBS

EAST: No. 5 Oregon (24-9) vs. No. 12 Liberty (28-6), 9:10 p.m., truTV